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If you mean that the boy dog is panting and whining whilst your female dog is in heat - then yes this can happen - HOWEVER if really really panting to the point of looking tired then it is not normal and the boy dog may have spiked a temperature in which case you need to get him to vet ASAP - this happened to my large breed dog and he had to have emergency ice baths at the vets to bring his temperature down fast to avoid him fitting or worse - so if it is constant and not occasional check his temp or go to a vet to check it. 
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